| 442 | For adult patients with severe (see note 1 below) chronic (see note 2 below) hand eczema AND unresponsive to an 8 week course of high potency topical corticosteroids.
1. Severe defined based on the Physician Global Assessment (PGA), including:
- At least one of the following cardinal features present at baseline as moderate or severe: erythema, scaling, hyperkeratosis/lichenification; and
- one of the following features present as severe: vesiculation, edema, fissures, pruritus/pain; and
- with an area of greater than 30% of affected hand surface
2. Chronic defined as:
- persists for greater than 3 months; OR
- reoccurs greater than or equal to 2 times within 12 months |
