Therapeutic Note(s)

For the treatment of schizophrenia or schizoaffective disorders in patients who have: A history of non-adherence AND One of the following: a) Inadequate control or significant side-effects from two or more formulary oral antipsychotic medications, including at least one atypical agent; OR b) Inadequate control or significant side-effects from one or more conventional depot antipsychotic agents. AND Adequate treatment of using 1-month paliperidone palmitate prolonged-release injectable suspension has been established for at least four months.