Therapeutic Note(s) |
10mg Tab (DAPAGLIFLOZIN)
Added on to metformin for patients:
- Who have inadequate glycemic control on metformin and
- Who have a contraindication or intolerance to a sulfonylurea or
- For whom insulin is not an option.
Added on to a sulfonylurea for patients:
- Who have inadequate glycemic control on a sulfonylurea and
- Who have a contraindication or intolerance to metformin or
- For whom insulin is not an option.
For the treatment of adult patients with New York Heart Association (NYHA) class II and III heart failure, as an adjunct to standard of care therapy, for the treatment of heart failure with reduced ejection fraction (HFrEF) [Left ventricular ejection fraction (LVEF less than or equal to 40%)]. Standard of care therapies include beta-blockers, angiotensin converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs), plus a mineralocorticoid receptor antagonist.